Immunological methods of diagnosis in giardiasis: an overview.
نویسنده
چکیده
The epidemiology and clinical presentations of giardiasis are reviewed to provide a basis of understanding the laboratory aspects of this parasitic infection. Diagnosis is then discussed in light of recent studies that challenge our overall approach to the diagnosis of enteric parasites and demonstrate the need for further evaluation on the basis of cost-effectiveness as well as reliability and clinical practicality. Overall effectiveness as well as the difficulties with present standard diagnostic methods in giardiasis are reviewed. This is followed by a discussion of the more recently developed immunological approaches to diagnosis. The role of these tests in the parasitology laboratory is also discussed.
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Background & Aim: Human giardiasis is an infection produced by the flagellate protozoan, giardia lamblia, that is localized to the small bowel where it produces damage to the mucosa with or without gastrointestinal symptoms. This parasitosis has a worldwide distribution. Its incidence varies from 15 to 30%. Current evidence suggests that both humoral and cellular immune responses are involv...
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ورودعنوان ژورنال:
- Annals of clinical and laboratory science
دوره 21 2 شماره
صفحات -
تاریخ انتشار 1991